課程介紹
本課程將介紹分子與細胞生物學對於生物醫學之影響,內容將著重於細胞功能之調控與疾病的關聯、在疾病診斷、治療或預防上的應用等,期能促進學生了解分子醫學的概念及進一步探索相關領域的熱忱。課程中包含論文實例探討,並視情況安排學生校外參訪或邀請校外講員至課堂上交流。
The objective of this course is to deliver the basic concept of molecular medicine to undergraduates. The course will introduce the great impact of molecular cell biology on the progress in medicine, with focuses on the regulation of cell function, cell-cell communication, the pathogenesis of diseases, and recent advances in medical application. The students will be encouraged to further explore the related field after the course.
教科書:
教師自編講義可自iLearning下載 (Instructor-arranged handouts are free to download from iLearning)
教學進度:
1. 甚麼是分子醫學 Introduction to Molecular Medicine
2. 基因的奧秘:如何促使或抑制基因的表現 Induction or inhibition of gene expression
3. 生命的分子網絡:蛋白質之交互作用與訊息傳遞 Detecting and analyzing protein-protein interactions
4. 找尋疾病標誌:體學技術之應用 Application of Omics approaches for disease biomarker discovery
5. 如何製作重組蛋白質:漫談蛋白質之表現與純化 Protein expression and purification
6. 觀察即是美:光學顯微鏡之應用 Microscopy at many levels
7. 單元抗體技術學於疾病診斷之應用 Application of monoclonal antibodies in diagnosis of diseases
8. 利用PCR進行動物疾病檢測 PCR-based techniques for diagnosis of animal diseases
9. 病毒載體與基因治療 Viral vector for gene therapy
10. 病毒載體疫苗 Viral vector for vaccine development
11. 精準醫療在獸醫學的應用 Precision medicine in veterinary medicine
本課程不開放報名