課程介紹

Cellular Signal Transduction and Regulation                                                2018/2/21

時間:      週五 9:10-11:00 AM

地點:     獸醫館 414室  

Lecture

Content

1

Cell Signaling: Introduction

2

G Protein-Coupled Signal Transduction Pathway*

3

Intracellular Messenger Substances: Second Messengers*

4 (4/2)

Midterm Examination I (Lectures 1 - 3)

5

Signal Transmission via Receptors with Intrinsic Tyrosine Kinase Activity*

6

Ser/Thr-Specific Protein Kinases and Protein Phosphatases*

7

Membrane Receptors with Associated Tyrosine Kinase Activity

8

Other Types of Receptors

9 (5/18)

Midterm Examination II (Lectures 5 - 8)

10

NF-κB Signaling Pathway

11

Discussion of Research Article

12

Extrinsic Apoptotic Pathway

13

Intrinsic Apoptotic Pathway

14

Discussion of Research Article

15

Student Presentation

16 (6/29)

Final Examination (Lectures 10 - 15)

 

上課教材:

  1. Biochemistry of Signal Transduction and Regulation, 4th ed., 2008, Gerhard Krauss, Wiley-VCH Verlag GmbH. (3rd ed. eBook)
  2. Cell Signalling, 3rd ed., 2010, J. T. Hancock, OxfordUniversity Press.
  3. Structure and Function in Cell Signaling, 2008, J. Nelson, John Wiley & Sons.
  4. Signal Transduction: Pathways, Mechanisms and Diseases, 2010, Ari Sitaramayya, Springer-Verlag BerlinHeidelberg.
  5. Signal Transduction, 3rd ed., 2016, I. M. Kramer, Academic Press, Elsevier. (eBook)
  6. Journal Articles.

課程講義: 每週上課前公佈於iLearning，請自行下載列印。

 

成績評量:

(1) 兩次期中考試各佔25％，期末考佔25％，文獻討論及報告佔25%。

(2) 因故未參與文獻討論者，需針對討論文獻撰寫700至1,000字中文摘要，並於討論課後一週(內)繳交。未繳交者視同缺考以零分計。

(3) 口頭報告時應以簡報檔(PPT或PDF)輔助說明，報告完後需繳交檔案作為評分依據。
 
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