課程介紹

課程名稱

(course name)

(中) 動物毒物病理學 (二)

(Eng.) Toxicologic Pathology in Animals (II)

開課單位

(offering dept.)

獸醫病理生物學研究所

課程類別

(course type)

□必修   þ選修

學分

(credits)

2

授課教師

(teacher)

廖俊旺

選課單位

(department)

碩士班一年級

授課語言

(language)

中文

開課學期

(semester)

下學期

課程簡述

(course description)

(中) 本課程將介紹有關毒性藥物及化學物質對體內各系統器官所產生之非增殖性及增殖性(腫瘤)病理變化及理論，包括：神經系統、心血管、血液、泌尿、消化、骨骼、肌肉、內分泌、生殖、感官系統等體內各器官所引起之細胞病理變化及病理學評估之介紹。

(Eng.) This course will introduce the systemic alterations of non-proliferative and proliferative (tumor) lesions of drugs and chemicals in body, including nervous, cardiovascular, urinary, digestive, skeletal muscular, reproductive, and integument systems in animals will be discussed.

先修課程名稱

(prerequisites)

 

課程目標與核心能力關聯配比(%)

(relevance of course objectives and core learning outcomes)   

課程目標之教學方法與評量方法

(teaching and assessment methods for course objectives)

課程目標

核心能力

配比(%)

教學方法

評量方法

(中) 毒物病理學(二)為綜合毒理學與病理學之研究，主要探討毒物對體內各系統之細胞結構所引起之非增殖性及增殖性(腫瘤)之病變及作用機制，並提供毒物影響之整體評估概念。

(Eng.) Advance toxicologic pathology (II) in animals is used to elucidate the non- proliferative and proliferative (tumor) lesions and mechanisms of toxicants in various systems of animals. The aims of this course will provide and promote student’s logics and study conceptions in the toxicity research.
  1. 應用動物醫學、病理學及生物醫學專業知能。
  2. 獸醫病理學、微生物學及生物醫學之實驗操作技術。
  3. 生物醫學訓練、致病機理研究及疫苗生技研發技術等關鍵能力的培養。
  4. 研究方向的釐定、問題發想與分析、邏輯推理及溝通技巧的應用。

50

 

 

 

10

 

 

 

 

20

 

 

 

 

 

 

20

 

 

講授(teaching)

討論/報告(discussion & report)

期中及期末考試
教科書:
  1. Casarett & Doull’s Toxicology. 2002. The Basic Science of Poisons, Klaassen, C. D. Ed., 6th ed., International Edition, McGraw-Hill, New York, USA.
  2. Mann, P.C., Hardisty, J. F., and Parker, M.D. 2001. Handbook of Toxicologic Pathology, Haschek, W. M., Rousseaux, C.G., and Wallig, M. A., Eds., Two-Volume Set, pp. 187-206, Elsevier Science & Technology Books.
  3. Society of Toxicologic Pathology (STP). 2012. International Harmonization of Toxicologic Pathology Nomenclature: An Overview and Review of Basic Principles. Toxicologic Pathology.
  4. The INHAND Project. 2012. International harmonization of nomenclature and diagnostic criteria for lesions in rats and mice. Proliferative and Nonproliferative Lesions of the Rat and Mouse. Toxicologic Pathology.
教學進度:
  1. 毒性病理學名詞簡介(International Harmonization of Toxicologic Pathology Nomenclature)
  2. 肝臟系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the hepatobiliary system)
  3. 膽管系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the hepatobiliary system)
  4. 腎臟系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the urinary system)
  5. 膀胱系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the urinary system)
  6. 呼吸系統毒性及腫瘤病變Proliferative and nonproliferative lesions of the respiratory System)
  7. 雄性生殖系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the male reproductive system )
  8. 雌性生殖系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the female reproductive system )
  9. 期中考 (Mid-term examination)
  10. 乳腺及其他腺體系統毒性及腫瘤病變(Proliferative and nonproliferative lesions of the mammary, Zymbal's, preputial glands)
  11. 神經系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the nervous system)
  12. 心血管系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the cardiovascular system)
  13. 血液系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the hematological system)
  14. 骨骼系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the bone system)
  15. 肌肉系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the muscular system)
  16. 內分泌系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the endocrine system
  17. 感官系統毒性及腫瘤病變(Non-proliferative and proliferative lesions of the sensory system
  18. 期末考 (Final-term examination)
本課程不開放報名